Timolol maleate
- CAS Number: 26921-17-5
- Molecular Formula: C₁₃H₂₄N₄O₃S·C₄H₄O₄ (or simplified as C₁₇H₂₈N₄O₇S)
- Molecular Weight: 432.49-432.50 g/mol
- Appearance: White to off-white crystalline powder, which is odorless and has a bitter taste.
- Solubility: Soluble in water, methanol, and alcohol; slightly soluble in ethanol; insoluble in chloroform, cyclohexane, and ether.
描述
Timolol maleate (CAS: 26921-17-5) is a non-selective β-adrenergic antagonist with the molecular formula C₁₇H₂₈N₄O₇S (anhydrous) and a white crystalline powder appearance. It is primarily used as an antihypertensive and antiglaucoma agent, reducing intraocular pressure by inhibiting aqueous humor production. Common side effects include bradycardia and bronchospasm, while contraindications include asthma and heart failure. The drug is often combined with other therapies for chronic open-angle glaucoma。
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