Gentamicin sulfate

描述

Gentamicin sulfate is a broad-spectrum aminoglycoside antibiotic derived from fermentation of Micromonospora spp., widely used as an API in pharmaceutical formulations to treat severe Gram-negative bacterial infections. As a hygroscopic white to off-white powder, it exhibits high water solubility and chemical stability under recommended storage conditions (pH 3.5–5.5 in aqueous solutions). Its molecular complexity—represented by formulas like C₂₁H₄₃N₅O₇·H₂SO₄—reflects its composition as a mixture of related gentamicin components (C1, C1a, C2). Recognized by CAS number 1405-41-0, this API is critical in injectable, topical, and ophthalmic preparations due to its potent bactericidal activity against resistant pathogens。