Salbutamol Sulfate
Chemical Name: Salbutamol sulfate (also known as albuterol sulfate)
CAS No.: 51022-70-9
Molecular Formula: C₁₃H₂₁NO₃·½H₂SO₄ (hemisulfate salt) or (C₁₃H₂₁NO₃)₂·H₂SO₄ (dihydrate)
Molecular Weight: 288.35 g/mol (hemisulfate) or 576.70 g/mol (dihydrate)
Appearance: White crystalline powder or colorless to slightly yellow liquid (in solution)
Synonyms: Albuterol sulfate, Ventolin sulfate, Salbutamol hemisulfate
描述
Salbutamol sulfate (CAS: 51022-70-9), a selective β2-adrenergic receptor agonist, is a white crystalline powder with the molecular formula C13H21NO3·½H2SO4 and a molecular weight of 288.35 g/mol. It is widely used as an active pharmaceutical ingredient (API) in bronchodilators for treating asthma, chronic obstructive pulmonary disease (COPD), and other reversible airway obstructions. The drug exhibits high water solubility (50 mg/mL in 1M NaOH) and is typically stored at 2-8°C to maintain stability. As a first-line β2-agonist, it demonstrates rapid onset of action (within 3-5 minutes via inhalation) and sustained bronchodilation effects。
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